As part of prep for my annual physical in March 2024, on 12/13/2023 my GP had a set of labs done by Quest Labs here in Granbury,TX. One of the labs we are always interested in is how my Testosterone levels are doing. The lead graphic above shows that they have varied since 2018, and my results yesterday indicated they were above the upper bound at 935 or so. Keep in mind that every two weeks I am injected with a 1 ml Testosterone shot so for me, this is not unexpected. My last shot was Sunday a week ago.

Here’s the rest of the story. In our society, we talk in hushed voices about women and their “hot flashes” and even, God bless us, Hormone Replacement Theory. What we NEVER talk about, even among men in the locker room, so to speak, is men and their testosterone levels. Among men, testosterone is inexplicably tied to their perceived sexual prowess, and any discussion along the lines of lack thereof is taboo. It directly attacks their manhood.

This is tragic in that testosterone in men has many many more functions than growing hair on their chests. It extends further than this to severely impacting those of us (males) on peritoneal dialysis. To help in this area, I turned to my AI assistant Poe with the following Prompt and results. Please read what she has to say, and my comments thereafter. Listen up Fresenius Dialysis Team; you are brought to task therein:

Prompt: Write a 500 word blog in a serious tone on how important testosterone is to male patients on peritoneal dialysis.

Assistant Assistant Poe

Title: The Significance of Testosterone for Male Patients on Peritoneal Dialysis

Introduction

Peritoneal dialysis is a life-saving treatment for individuals with end-stage renal disease (ESRD). While it offers numerous benefits, it can also have an impact on hormone levels in the body. Specifically, male patients on peritoneal dialysis may experience a decline in testosterone levels. In this blog post, we will explore the importance of testosterone in male patients and shed light on the significance of managing testosterone levels for those undergoing peritoneal dialysis.

Understanding Testosterone

Testosterone is a hormone primarily associated with male sexual development and reproductive function. However, its influence extends far beyond these realms. It plays a crucial role in regulating bone density, muscle mass, red blood cell production, mood, cognitive function, and overall well-being. Testosterone levels naturally decline with age, but in male patients on peritoneal dialysis, this decline may be accelerated due to various factors.

Testosterone and Peritoneal Dialysis

Peritoneal dialysis involves the use of a catheter to filter waste products and excess fluids from the body. While it is an effective treatment, it can lead to hormonal imbalances. The loss of proteins during dialysis can disrupt the delicate equilibrium of hormones, including testosterone. Additionally, factors such as inflammation, oxidative stress, and the presence of comorbidities can further contribute to decreased testosterone levels in these patients.

Impact on Male Patients

The decline in testosterone levels can have significant consequences for male patients on peritoneal dialysis. Firstly, it can lead to a decrease in muscle mass and strength, resulting in fatigue and reduced physical performance. This can impact the patient’s ability to carry out daily activities, diminish their quality of life, and potentially lead to muscle wasting. Moreover, low testosterone levels may contribute to decreased bone mineral density, increasing the risk of osteoporosis and fractures.

Furthermore, testosterone deficiency can affect mood and cognitive function. Male patients may experience symptoms such as depression, irritability, difficulty concentrating, and reduced motivation. These changes can further hinder their ability to participate in social activities and negatively impact their mental well-being.

Managing Testosterone Levels

Recognizing the importance of testosterone in male patients on peritoneal dialysis, it is crucial to monitor and manage testosterone levels effectively. Regular assessment of hormone levels can help identify deficiencies and guide appropriate interventions. Healthcare professionals may consider various treatment options, including testosterone replacement therapy (TRT).

TRT involves the administration of testosterone to supplement or restore levels in the body. It can be administered through different methods, such as injections, gels, patches, or pellets. However, it is essential to evaluate each patient individually and consider potential risks and benefits before initiating TRT.

In addition to TRT, optimizing lifestyle factors can also play a role in managing testosterone levels. Regular exercise, a balanced diet, stress reduction techniques, and adequate sleep can positively influence hormone production and overall well-being.

Conclusion

Testosterone is a vital hormone for male patients on peritoneal dialysis, as it impacts various aspects of their health and well-being. The decline in testosterone levels associated with this treatment can lead to muscle loss, decreased bone density, mood disturbances, and cognitive impairments. By actively monitoring testosterone levels and implementing appropriate interventions, healthcare professionals can help mitigate these adverse effects. It is crucial to individualize treatment plans and utilize a multidisciplinary approach to optimize the overall health and quality of life for male patients on peritoneal dialysis.

My closing comments for Fresenius Dialysis Team: It appears that monitoring testosterone levels for males is central to the overall care and feeding of your patients. Why has this never been a topic of interest or questioned by team members? What are you going to do about it? It would appear to be as central to a male patients’ well being as phosphorous, potassium or other chemical levels you keep a keen eye on?