A Michigan Medicine study found that the longer an individual has type 2 diabetes, the more likely they are to exhibit changes in brain structure, such as decreased cortical thickness and gray matter volumes. Despite no discernible difference in cognition between those with and without diabetes, complications like chronic kidney disease and vascular damage in diabetes are linked to these brain changes. They also note that diabetic complications increased the odds of developing a cognitive disorder by 2.45 times in 40 to 60-year-olds.
So what is being implied herein? Type 2 diabetes -> brain changes -> also kidney functions -> plus other externalities -> and cognitive functions, i.e., how well our brain works? We already have cited research in previous blogs associating CKF with diabetes. It is a given. Therefore, if diabetes is adversely affecting cognition, then diabetes leading to CKF also imparts to those on dialysis as a result of CKF as potentially having cognition impacted as a comorbidity.
Impact on Cognitive Function:
The impact of kidney disease on cognitive function can manifest in various ways. Studies have shown that individuals with kidney disease may experience:
Slowed Processing Speed: Cognitive processing speed, such as the ability to quickly understand and respond to information, may be impaired in individuals with kidney disease.
Reduced Attention and Concentration: Difficulty focusing, sustaining attention, and maintaining concentration are common cognitive challenges observed in some individuals with kidney disease.
Memory Problems: Kidney disease may affect different aspects of memory, including both short-term memory and long-term memory. This can manifest as forgetfulness, difficulty retaining new information, or trouble recalling past events.
Executive Function Deficits: Executive functions, which include skills like planning, organization, problem-solving, and decision-making, may be compromised in individuals with kidney disease.
Increased Risk of Cognitive Disorders: Research suggests that kidney disease, particularly in the presence of diabetes and its complications, may increase the risk of cognitive disorders such as dementia and Alzheimer’s disease.
Take it on board: It’s bad enough to experience CKF resulting in the need for dialysis. In the presence of diabetes which is highly likely, it is a double-edged sword. Perhaps having a “big brain” before onset is helpful?
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